The Tokyo Metropolitan Police Department creates a new division which consists of 5 female detectives. The new division is called Higanbana which is a flower with a poison root. The 5 female detective have their own specialties and sensitivities. The women try to solve a murder that took place at the wedding of a female doctor.
Detective Kinomiya Nagisa is a member of Higanbana. She has the special ability of sensing a criminal's murderous intent and ill will.